KMID : 0391520040120020144
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Journal of the Korean Child Neurology Society 2004 Volume.12 No. 2 p.144 ~ p.151
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A Cilinical Study of Diarrhea-Associated Benign Infantile Convulsion
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Lee Suk-Jin
Hwang Tae-Guy
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Abstract
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Purpose: The aim of this study is to reveal the detailed clinical features of diarrhea- associated benign infantile convulsion.
Methods: We studied 34 patients with diarrhea-associated benign infantile convulsion between March 2000 and February 2004.
Results: There were 34 patients with diarrhea-associated benign infantile convulsion : 19 boys and 15 girls. The age of the disease onset ranged from 3 to 34(mean; 18.7+/-6.6) months. The incidence was high from November to March. The types of the seizures were generalized tonic-clonic or generalized tonic in 32(94%) of 34 episodes, while the seizure types changed during episodes for 2 patients. The durations of seizures were from 3 sec to 10 min. 2 or more seizures occurred in 22(64.7%) episodes. A family history of febrile or afebrile convulsions was noted in 3 patients. There were no abnormalities in serum biochemistry tests. 12 out of 22 patients showed positive rotavirus antigen tests. Interictal EEG¡¯s were normal in 26 out of 30 episodes. CT or MRI demonstrated no neuroradiological abnormalities in 13 out of 14 patients. 4 patients experienced recurrence of diarrhea-associated benign infantile convulsion, but none had more than 2 episodes. Epilepsy developed in none of the patients during the follow-up period.
Conclusions: Diarrhea-associated benign infantile convulsion is characterized by a cluster of seizures. A continous or intermittent antiepileptic treatment is not required because recurrence or later development of epilepsy is rare. Appropriate treatment for a cluster of seizures will be the subject of future studies.
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KEYWORD
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Berign convulsion, Infant, Diarrhea
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